For research use only. Not for human consumption.

MOTS-C

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino-acid peptide encoded within the mitochondrial genome rather than the nuclear DNA.

Price range: $40.00 through $125.00

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What It Is

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino-acid peptide encoded within the mitochondrial genome rather than the nuclear DNA. Functioning as a mitochondrial-derived signaling peptide, it translocates to the nucleus under cellular stress to regulate nuclear gene expression and systemic metabolic homeostasis.

What It Is Commonly Used For

  • AMPK Activation & Metabolic Flexibility: Studied for its role in directly activating AMP-activated protein kinase (AMPK), stimulating cellular glucose uptake, and enhancing insulin sensitivity.

  • Exercise Mimetic & Performance Research: Evaluated in cellular and animal models for improving physical capacity, muscle endurance, and metabolic adaptation similar to exercise training.

  • Fat Oxidation & Weight Regulation: Researched for its capacity to prevent diet-induced obesity, accelerate fatty acid oxidation, and attenuate lipid accumulation in hepatic tissue.

General Purpose

To provide a mitochondria-derived signaling peptide for investigating AMPK pathways, exercise-mimetic metabolic adaptations, and systemic cellular homeostasis in laboratory research.

Specifications

Property Details
Product Name MOTS-c
Product Category Mitochondrial & Metabolic Peptides
Compound Type Mitochondria-Derived Peptide (MDP)
Primary Goal AMPK pathway activation, metabolic flexibility study, and glucose regulation
Form Lyophilized powder (vial)
Storage Store lyophilized powder at 2°C to 8°C (refrigerated) or -20°C for long-term storage. Protect from direct light.
Intended Use Laboratory Research Only

Additional information

Dosage

10MG, 40MG

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