What It Is
GLP-2 is an 33-amino acid peptide hormone co-secreted with GLP-1 by intestinal L-cells following nutrient ingestion. Unlike GLP-1, which primarily targets metabolic glycemic control, GLP-2 acts as a potent gut-trophic factor that specifically regulates intestinal mucosal growth, epithelial repair, and nutrient absorption pathways.
What It Is Commonly Used For
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Intestinal Mucosal Growth & Repair: Studied for its ability to stimulate crypt cell proliferation and inhibit enterocyte apoptosis, leading to increased mucosal mass and villus height in intestinal models.
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Gut Barrier Integrity: Evaluated for strengthening tight junction proteins, reducing intestinal permeability, and protecting mucosal tissues against inflammatory damage.
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Nutrient Absorption Efficiency: Researched in gastrointestinal models for enhancing intestinal blood flow and upregulating nutrient transporter expression.
General Purpose
To provide a specialized gastrointestinal trophic peptide for investigating intestinal epithelial regeneration, gut barrier homeostasis, and nutrient absorption mechanisms in laboratory research.
Specifications
| Property |
Details |
| Product Name |
GLP-2 (Glucagon-Like Peptide-2) |
| Product Category |
Gastrointestinal & Trophic Peptides |
| Compound Type |
Endogenous Intestinal Peptide Hormone |
| Primary Goal |
Mucosal proliferation, gut barrier optimization, and nutrient absorption study |
| Form |
Lyophilized powder (vial) |
| Storage |
Store lyophilized powder at 2°C to 8°C (refrigerated) or -20°C for long-term storage. Protect from direct light. |
| Intended Use |
Laboratory Research Only |