For research use only. Not for human consumption.
5-Amino-1MQ is a synthetic small-molecule methylquinolinium derivative that functions as a selective inhibitor of Nicotinamide N-methyltransferase (NNMT).
$55.00
5-Amino-1MQ is a synthetic small-molecule methylquinolinium derivative that functions as a selective inhibitor of Nicotinamide N-methyltransferase (NNMT). NNMT is a cytosolic enzyme that regulates cellular energy homeostasis, fat storage, and epigenetic methylation pathways by transferring methyl groups from S-adenosylmethionine (SAM).
Adipocyte Metabolism & Fat Mass Reduction: Studied for its ability to suppress NNMT activity in fat tissue, reducing lipogenesis and shrinking adipocyte volume without causing systemic appetite suppression.
Intracellular NAD+ & SAM Preservation: Evaluated for preventing NNMT-mediated degradation of nicotinamide, leading to elevated intracellular $\text{NAD}^+$ and S-adenosylmethionine (SAM) levels for improved mitochondrial ATP production.
Musculoskeletal Hypertrophy & Recomposition: Researched in metabolic models for supporting skeletal muscle cell regeneration, insulin sensitivity, and athletic recovery during caloric deficit states.
To provide a small-molecule NNMT enzyme inhibitor for investigating adipocyte energy balance, $\text{NAD}^+$ salvage pathways, cellular methylation dynamics, and metabolic disease interventions in laboratory research.
| Property | Details |
| Product Name | 5-Amino-1MQ (5-Amino-1-methylquinolinium) |
| Product Category | Enzyme Inhibitors & Small Molecule Metabolic Compounds |
| Compound Type | Small-Molecule NNMT Inhibitor |
| Primary Goal | NNMT blockade, intracellular $\text{NAD}^+$ preservation, and metabolic research |
| Form | Lyophilized powder (vial) / Capsules |
| Storage | Store lyophilized powder at 2°C to 8°C (refrigerated) or -20°C for long-term storage. Protect from direct light. |
| Intended Use | Laboratory Research Only |
| Dosage | 10MG |
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