What It Is
PT-141, chemically known as Bremelanotide, is a synthetic cyclic peptide analog of alpha-Melanocyte-Stimulating Hormone (alpha-MSH). It is a active metabolite of Melanotan II that selectively targets central melanocortin receptors—primarily MC3R and MC4R—in the central nervous system without significantly inducing melanogenesis via MC1R.
What It Is Commonly Used For
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Central Neurological Sexual Pathways: Studied for its action in the hypothalamus to modulate central sexual desire and arousal mechanisms, independent of vascular or nitric oxide pathways.
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Melanocortin Receptor Signaling: Evaluated in neurological models to map selective MC3R and MC4R agonist activity in the brain.
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Dopaminergic System Interaction: Researched for its indirect downstream interaction with central dopaminergic pathways that regulate motivation and reward behaviors.
General Purpose
To provide a selective melanocortin receptor agonist for investigating central nervous system control of sexual behavior, hypothalamic signaling pathways, and neuro-endocrine response mechanisms in laboratory research.
Specifications
| Property |
Details |
| Product Name |
PT-141 (Bremelanotide) |
| Product Category |
Melanocortin Receptor Agonists & Neuropeptides |
| Compound Type |
Synthetic Cyclic Peptide Fragment |
| Primary Goal |
Central MC3R/MC4R binding, hypothalamic neurotransmission, and behavioral research |
| Form |
Lyophilized powder (vial) |
| Storage |
Store lyophilized powder at 2°C to 8°C (refrigerated) or -20°C for long-term storage. Protect from direct light. |
| Intended Use |
Laboratory Research Only |